46 days in Italy Itinerary

46 days in Italy Itinerary

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Route & dates

46 days in Italy Itinerary

Start: Pittsburgh
Fly:  13​h 45​min
1
Rome
— 5 nights
train:  1​h 15​min
2
Naples
— 5 nights
subway + taxi:  1​h 30​min
3
Amalfi
— 5 nights
Drive:  4​h 30​min
4
Assisi
— 5 nights
Drive:  1​h 45​min
5
Siena
— 5 nights
bus:  1​h 15​min
6
Florence
— 6 nights
train:  2​h 15​min
7
Venice
— 5 nights
bus:  1​h 30​min
8
Verona
— 5 nights
train:  1​h 15​min
9
Milan
— 3 nights
Fly:  13​h 30​min
End: Pittsburgh

5
nights
Rome

Rome ©
Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.
Rome is known for historic sites, nightlife, museums, classes, and shopping. Your plan includes some of its best attractions: explore the ancient world of Colosseum, make a trip to Trevi Fountain, take in the spiritual surroundings of Vatican Museums, and admire the striking features of Pantheon.

To see photos, where to stay, other places to visit, and tourist information, read our Rome attractions planner.

Pittsburgh, USA to Rome is an approximately 14-hour flight. You can also do a combination of train and flight; or do a combination of bus and flight. Due to the time zone difference, you'll lose 6 hours traveling from Pittsburgh to Rome. Traveling from Pittsburgh in October, things will get a bit warmer in Rome: highs are around 73°F and lows about 55°F. Finish your sightseeing early on the 12th (Mon) to allow enough time to take a train to Naples.

Things to do in Rome

Historic Sites Museums Tours

Side Trip

Vatican City
Find places to stay Oct 6 — 12:
Highlights from your plan
Colosseum ©
Colosseum
Pantheon ©
Pantheon
St. Peter's Basilica ©
St. Peter's Basilica

5
nights
Naples

Naples ©
Naples is the capital of the Italian region Campania and the third-largest municipality in Italy after Rome and Milan. Explore Naples' surroundings by going to Paestum Ruins (in Paestum), Cilento (in Salerno) and Le Vigne di Raito (in Vietri sul Mare). There's lots more to do: delve into the distant past at Pompeii Archaeological Park, admire the landmark architecture of Villa dei Misteri, see what you can catch with a fishing tour, and make a trip to Via San Gregorio Armeno.

For more things to do, other places to visit, ratings, and more tourist information, use the Naples trip itinerary maker .

Getting from Rome to Naples by train takes about 1.5 hours. Other options: drive; or take a bus. In October in Naples, expect temperatures between 74°F during the day and 58°F at night. Wrap up your sightseeing on the 17th (Sat) to allow time to travel to Amalfi.

Things to do in Naples

Tours Outdoors Historic Sites

Side Trips

Sorrento, Pompeii, Positano, Paestum Ruins, Cilento
Find places to stay Oct 12 — 17:
Highlights from your plan
Le Vigne di Raito ©
Le Vigne di Raito
Pompeii Archaeological Park ©
Pompeii Archaeological Park
Food Tours

5
nights
Amalfi

Known for its impressive hillside cascade of colorful stone buildings down to the Mediterranean shore, Amalfi is the cultural and commercial heart of southern Italy's Amalfi Coast.
You'll find plenty of places to visit near Amalfi: Positano (Il Sentiero Degli Dei, Walk of the Gods, & more), I Suoni degli Dei - Pelagos (in Praiano) and Monte Finestra (in Tramonti). The adventure continues: savor the flavors at Food & Drink, get interesting insight from Tours, take in nature's colorful creations at Villa Cimbrone Gardens, and take in the spiritual surroundings of Cloister del Paradiso.

To see ratings, maps, traveler tips, and other tourist information, go to the Amalfi trip planner.

Traveling by combination of subway and taxi from Naples to Amalfi takes 1.5 hours. Alternatively, you can drive; or take a bus. In October, daytime highs in Amalfi are 73°F, while nighttime lows are 63°F. Finish up your sightseeing early on the 22nd (Thu) so you can go by car to Assisi.

Things to do in Amalfi

Outdoors Parks Tours

Side Trips

Ravello, Positano, Praiano, Monte Finestra, Chiesa di San Pancrazio Martire
Find places to stay Oct 17 — 22:
Highlights from your plan
Wine Tours & Tastings
Il Sentiero Degli Dei ©
Il Sentiero Degli Dei
Fornillo ©
Fornillo

5
nights
Assisi

Assisi ©
Rich in culture and religious tradition, Assisi is known as the birthplace of St.
Venture out of the city with trips to Montioni Frantoio e Cantina (in Montefalco), Vineria del Carmine (in La Bruna) and Castello Monte Vibiano Vecchio (in Mercatello). There's much more to do: pause for some serene contemplation at Basilica Papale e Sacro Convento di San Francesco d'Assisi, take in the spiritual surroundings of Eremo delle Carceri, do a tasting at Tili Vini Societa Agricola, and stroll around Mount Subasio.

For ratings, maps, photos, and other tourist information, refer to the Assisi online trip builder .

Traveling by car from Amalfi to Assisi takes 4.5 hours. Alternatively, you can take a train; or do a combination of bus and train. Traveling from Amalfi in October, Assisi is little chillier at night with lows of 51°F. Wrap up your sightseeing on the 27th (Tue) to allow time to drive to Siena.

Things to do in Assisi

Historic Sites Wineries Museums

Side Trips

Perugia, Montioni Frantoio e Cantina, Castello Monte Vibiano Vecchio, Museo Cinema a Pennello
Find places to stay Oct 22 — 27:
Highlights from your plan
Tili Vini Societa Agricola ©
Tili Vini Societa Agricola
Eremo delle Carceri ©
Eremo delle Carceri

5
nights
Siena

Siena, a medieval Tuscan city, features numerous attractions, including a historic town center, alleyways, towers, and well-preserved buildings.
Change things up with these side-trips from Siena: Guardastelle Vineyard (in San Gimignano), Montalcino (Castiglion del Bosco & Podere Il Cocco) and Ciacci Piccolomini d'Aragona (in Castelnuovo dell'Abate). There's much more to do: indulge your senses at some of the top wineries in the area, take in the spiritual surroundings of Battistero di San Giovanni, make a trip to Piazza del Campo, and pause for some serene contemplation at Duomo di Siena.

To see traveler tips, where to stay, ratings, and tourist information, refer to the Siena online trip maker .

Traveling by car from Assisi to Siena takes 2 hours. Alternatively, you can take a bus; or take a train. Expect a daytime high around 73°F in October, and nighttime lows around 56°F. Cap off your sightseeing on the 1st (Sun) early enough to catcht the bus to Florence.

Things to do in Siena

Wineries Historic Sites Tours

Side Trips

Montalcino, Guardastelle Vineyard
Find places to stay Oct 27 — Nov 1:
Highlights from your plan
Wine Tours & Tastings
Scuola di Cucina di Lella ©
Scuola di Cucina di Lella
Piazza del Campo ©
Piazza del Campo

6
nights
Florence

Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.
Get out of town with these interesting Florence side-trips: Leaning Tower of Pisa (in Pisa) and Castello del Trebbio (in Santa Brigida). There's much more to do: explore the world behind art at Gallerie Degli Uffizi, take in panoramic vistas at Campanile di Giotto, contemplate in the serene atmosphere at The Baptistery of St. John, and steep yourself in history at Cathedral of Santa Maria del Fiore.

To see maps, where to stay, reviews, and tourist information, you can read our Florence itinerary planning website .

Traveling by bus from Siena to Florence takes 1.5 hours. Alternatively, you can drive; or take a train. In November, daily temperatures in Florence can reach 61°F, while at night they dip to 46°F. Finish up your sightseeing early on the 7th (Sat) so you can catch the train to Venice.

Things to do in Florence

Museums Tours Historic Sites

Side Trips

Leaning Tower of Pisa, Castello del Trebbio
Find places to stay Nov 1 — 7:
Highlights from your plan
Food Tours
Gallerie Degli Uffizi ©
Gallerie Degli Uffizi
Academy Of Florence Art Gallery ©
Academy Of Florence Art Gallery

5
nights
Venice

Venice ©
Virtually unchanged for the last six centuries, Venice is actually a group of islands made famous by a series of canals, bridges, monuments, piazzas, and narrow pedestrian lanes.
Venture out of the city with trips to Padua (Scrovegni Chapel & Basilica di Sant’Antonio). And it doesn't end there: explore the activities along Canal Grande, hit the best photo ops around with an inspiring photography tour, examine the collection at Doge's Palace, and take in the views from Ponte dei Sospiri.

For traveler tips, maps, and other tourist information, use the Venice attractions planner .

Traveling by train from Florence to Venice takes 2.5 hours. Alternatively, you can drive; or take a bus. Traveling from Florence in November, you will find days in Venice are slightly colder (56°F), and nights are about the same (43°F). Wrap up your sightseeing on the 12th (Thu) early enough to take a bus to Verona.

Things to do in Venice

Historic Sites Museums Tours

Side Trip

Padua
Find places to stay Nov 7 — 12:
Highlights from your plan
Canal Grande ©
Canal Grande
Basilica di San Marco
Basilica di San Marco
Piazza San Marco ©
Piazza San Marco

5
nights
Verona

Verona ©
The famous setting for Shakespeare's star-crossed lovers, Romeo and Juliet, Verona is one of northern Italy's main tourist destinations, largely owing to its incredibly rich artistic heritage.
Verona is known for nightlife, historic sites, museums, nature, and parks. Your plan includes some of its best attractions: explore the ancient world of Arena di Verona, don't miss a visit to Piazza Bra, take in panoramic vistas at Torre dei Lamberti, and step into the grandiose world of Museo di Castelvecchio.

For photos, traveler tips, ratings, and more tourist information, read our Verona trip planner.

Take a bus from Venice to Verona in 1.5 hours. Alternatively, you can drive; or take a shuttle. In November in Verona, expect temperatures between 54°F during the day and 41°F at night. Cap off your sightseeing on the 17th (Tue) early enough to catch the train to Milan.

Things to do in Verona

Historic Sites Tours Wineries
Find places to stay Nov 12 — 17:
Highlights from your plan
Arena di Verona ©
Arena di Verona
Piazza delle Erbe ©
Piazza delle Erbe
Basilica di San Zeno Maggiore ©
Basilica di San Zeno Maggiore

3
nights
Milan

Milan ©
In many ways the most modern of Italian cities, Milan is a busy, elegant metropolis with an impressive list of grand palaces, fine churches, and important museums.
You'll find plenty of places to visit near Milan: Villa del Balbianello (in Tremezzina) and Museo Egizio (in Turin). There's lots more to do: contemplate in the serene atmosphere at Duomo di Milano, stroll the grounds of Monumental Cemetery, browse the collection at Pinacoteca Ambrosiana, and admire the landmark architecture of Galleria Vittorio Emanuele II.

To find more things to do, maps, photos, and tourist information, you can read our Milan trip builder .

Take a train from Verona to Milan in 1.5 hours. Alternatively, you can drive. In November, plan for daily highs up to 55°F, and evening lows to 42°F. Finish your sightseeing early on the 20th (Fri) to allow enough time to travel back home.

Things to do in Milan

Historic Sites Museums Fun & Games

Side Trips

Villa del Balbianello, Museo Egizio
Find places to stay Nov 17 — 20:
Highlights from your plan
Duomo di Milano ©
Duomo di Milano
Galleria Vittorio Emanuele II ©
Galleria Vittorio Emanuele II
Villa del Balbianello ©
Villa del Balbianello

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