60 days in Caribbean, Mexico, Central America & South America Itinerary

60 days in Caribbean, Mexico, Central America & South America Itinerary

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Route & dates

1
Nassau, Bahamas
— 3 nights
2
Havana, Cuba
— 4 nights
3
Mexico City, Mexico
— 5 nights
4
Granada, Nicaragua
— 1 night
5
La Fortuna de San Carlos, Costa Rica
— 4 nights
6
Manuel Antonio, Costa Rica
— 4 nights
7
Panama City, Panama
— 1 night
8
San Andres Island, Colombia
— 2 nights
9
Cartagena, Colombia
— 3 nights
10
Los Roques National Park, Venezuela
— 1 night
11
Quito, Ecuador
— 3 nights
12
Cusco, Peru
— 4 nights
13
Uyuni, Bolivia
— 1 night
14
San Pedro de Atacama, Chile
— 3 nights
15
San Carlos de Bariloche, Argentina
— 4 nights
16
Punta del Este, Uruguay
— 2 nights
17
Ciudad Del Este, Paraguay
— 1 night
18
Florianopolis, Brazil
— 4 nights
19
Brasilia, Brazil
— 3 nights

3
nights
Nassau, Bahamas

Nassau ©
On a trip to Nassau you can immerse yourself in a dynamic city atmosphere or spend your days lazing on the soft golden sands.
You'll explore the less-touristy side of things at Cable Beach and Pirates of Nassau Museum. There's still lots to do: steep yourself in history at Queen's Staircase, get some thrills on the water with a speed boat tour, brush up on your knowledge of spirits at John Watling's Distillery, and observe the fascinating underwater world at Marine Habitat at Atlantis.

To find where to stay, more things to do, photos, and tourist information, refer to the Nassau trip itinerary maker.

Lyon, France to Nassau is an approximately 17-hour flight. Traveling from Lyon to Nassau, you'll gain 6 hours due to the time zone difference. When traveling from Lyon in September, plan for a bit warmer days and much warmer nights in Nassau: temperatures range from °C by day to °C at night. Finish up your sightseeing early on the 4th (Fri) so you can travel to Havana.

Things to do in Nassau

Parks Outdoors Zoos & Aquariums

Side Trip

Marine Habitat at Atlantis
Find places to stay Sep 1 — 4:
Highlights from your plan
Cable Beach ©
Cable Beach
Queen's Staircase ©
Queen's Staircase
Speed Boats Tours

4
nights
Havana, Cuba

Havana ©
Cuba's capital and major commercial center, Havana manages to be very old and very modern at the same time.
Discover out-of-the-way places like Sirena Beach and Plaza de San Francisco. Finca Vigía and El Morro will appeal to history buffs. When in Havana, make a side trip to see Playa Paraiso in Cayo Largo, approximately Cayo Largo away. There's much more to do: explore the world behind art at Museu Nacional de Belas Artes de Cuba, make a trip to Plaza de la Catedral, contemplate in the serene atmosphere at Havana Cathedral, and contemplate the long history of Revolution Plaza Havana.

For reviews, ratings, and tourist information, you can read our Havana trip builder site.

You can fly from Nassau to Havana in 4.5 hours. Traveling from Nassau in September, Havana is little chillier at night with lows of °C. Wrap up your sightseeing on the 8th (Tue) early enough to travel to Mexico City.

Things to do in Havana

Outdoors Parks Beaches

Side Trip

Cayo Largo
Find places to stay Sep 4 — 8:
Highlights from your plan
Sirena Beach ©
Sirena Beach
Finca Vigía ©
Finca Vigía
Plaza de San Francisco ©
Plaza de San Francisco

5
nights
Mexico City, Mexico

Mexico City ©
Breathtakingly large, Mexico City provides a home for almost 9 million people living in nearly 1,700 distinct neighborhoods.
Rosary Chapel (Capilla del Rosario) and Paseo de la Reforma are good opportunities to explore the local culture. Museo Memoria y Tolerancia and Museo del Ejercito y Fuerza Aerea Mexicanos Bethlemitas will appeal to museum buffs. Get out of town with these interesting Mexico City side-trips: Puebla (Museo de la Evolucion Puebla (Museum of Evolution Puebla) & Templo de San Francisco). The adventure continues: steep yourself in history at Metropolitan Cathedral (Catedral Metropolitana), take in the spiritual surroundings of Iglesia de San Francisco, see the interesting displays at Museo Soumaya, and pause for some serene contemplation at Basilica de Santa Maria de Guadalupe.

To see photos, other places to visit, traveler tips, and more tourist information, go to the Mexico City holiday site.

Fly from Havana to Mexico City in 6.5 hours. You'll gain 1 hour traveling from Havana to Mexico City due to the time zone difference. Expect slightly colder temperatures when traveling from Havana in September; daily highs in Mexico City reach °C and lows reach °C. Cap off your sightseeing on the 13th (Sun) early enough to travel to Granada.

Things to do in Mexico City

Historic Sites Museums Neighborhoods

Side Trip

Puebla
Find places to stay Sep 8 — 13:
Highlights from your plan
Rosary Chapel (Capilla del Rosario) ©
Rosary Chapel (Capilla del Rosario)
Museo Soumaya ©
Museo Soumaya
Museo del Templo Mayor ©
Museo del Templo Mayor

1
night
Granada, Nicaragua

Granada ©
The lakeside city of Granada has the look and feel of a historically important economic and political center, with grand colonial architecture, a unified look, and many cultural attractions.
Start off your visit on the 14th (Mon): pause for some serene contemplation at Catedral de Granada, take in the architecture and atmosphere at Iglesia de La Merced, and then step off the mainland to explore Islets of Granada.

To see where to stay, more things to do, traveler tips, and tourist information, read Granada trip builder website.

You can fly from Mexico City to Granada in 7 hours. Another option is to drive. Finish your sightseeing early on the 14th (Mon) to allow enough time to drive to La Fortuna de San Carlos.

Things to do in Granada

Historic Sites Parks Nature
Find places to stay Sep 13 — 14:
Highlights from your plan
Catedral de Granada ©
Catedral de Granada
Iglesia de La Merced ©
Iglesia de La Merced
Islets of Granada ©
Islets of Granada

4
nights
La Fortuna de San Carlos, Costa Rica

La Fortuna de San Carlos ©
Set against the backdrop of the imposing Arenal Volcano, La Fortuna de San Carlos offers visitors a chance to explore diverse natural landscapes and sample some delicious local produce.
Get in touch with nature at Ecotermales Fortuna and Arenal Natura Ecological Park. Eschew the tourist crowds and head to Off-Road Tours and Rio Chollin. And it doesn't end there: get a new perspective on things with Boat Tours & Water Sports, take a memorable tour with Tours, and take in the natural beauty of Tabacon Hot Springs.

Plan my trip to La Fortuna de San Carlos with suggested itineraries provided by Inspirock.

Drive from Granada to La Fortuna de San Carlos in 5 hours. Alternatively, you can do a combination of shuttle and bus; or take a bus. Cap off your sightseeing on the 18th (Fri) early enough to go by car to Manuel Antonio.

Things to do in La Fortuna de San Carlos

Parks Nature Outdoors
Find places to stay Sep 14 — 18:
Highlights from your plan
Tabacon Hot Springs ©
Tabacon Hot Springs
Arenal Natura Ecological Park ©
Arenal Natura Ecological Park
Ecotermales Fortuna ©
Ecotermales Fortuna

4
nights
Manuel Antonio, Costa Rica

The rainforest meets the sea at Manuel Antonio National Park, a small but scenic natural preserve on the west coast of Costa Rica.
Get in touch with nature at Zipline and Kayaking & Canoeing. Explore hidden gems such as Canyoning & Rappelling Tours and Nature & Wildlife Tours. The adventure continues: tour the pleasant surroundings at Playa Biesanz.

For where to stay, other places to visit, ratings, and other tourist information, read our Manuel Antonio trip itinerary maker site.

You can drive from La Fortuna de San Carlos to Manuel Antonio in 4.5 hours. Alternatively, you can take a shuttle; or take a bus. Cap off your sightseeing on the 22nd (Tue) early enough to travel to Panama City.

Things to do in Manuel Antonio

Outdoors Tours Adventure

Side Trip

Jaco
Find places to stay Sep 18 — 22:
Highlights from your plan
Zipline
Nature & Wildlife Tours
Playa Biesanz ©
Playa Biesanz

1
night
Panama City, Panama

Panama City ©
Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.
On the 23rd (Wed), take an in-depth tour of Museo del Canal Interoceanico de Panama and then get to know the fascinating history of Avenida Balboa. Here are some ideas for day two: examine the collection at Biomuseo and then wander the streets of Cinta Costera.

To see ratings, more things to do, maps, and more tourist information, read Panama City itinerary planning app.

You can fly from Manuel Antonio to Panama City in 8 hours. Alternatively, you can drive; or take a bus. The time zone changes from Central Standard Time (CST) to Eastern Standard Time (EST), which is usually a 1 hour difference. September in Panama City sees daily highs of °C and lows of °C at night. Cap off your sightseeing on the 24th (Thu) early enough to travel to San Andres Island.

Things to do in Panama City

Neighborhoods Historic Sites Museums
Find places to stay Sep 22 — 24:
Highlights from your plan
Cinta Costera ©
Cinta Costera
Avenida Balboa ©
Avenida Balboa
Biomuseo ©
Biomuseo

2
nights
San Andres Island, Colombia

San Andres Island ©
The coral San Andres Island boasts a rich colonial history, exotic beaches, and a laidback, tropical lifestyle.
On the 25th (Fri), identify plant and animal life at La Piscinita and then see the vivid underwater world at West View. On your second day here, identify plant and animal life at Cayo El Acuario and then enjoy the sand and surf at Playa de Spratt Bight.

For other places to visit, reviews, traveler tips, and more tourist information, go to the San Andres Island visit app.

Getting from Panama City to San Andres Island by flight takes about 5 hours. In September in San Andres Island, expect temperatures between °C during the day and °C at night. Finish your sightseeing early on the 26th (Sat) to allow enough time to travel to Cartagena.

Things to do in San Andres Island

Parks Wildlife Outdoors
Find places to stay Sep 24 — 26:
Highlights from your plan
Cayo El Acuario ©
Cayo El Acuario
West View
West View
Playa de Spratt Bight ©
Playa de Spratt Bight

3
nights
Cartagena, Colombia

Cartagena ©
The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Do some cultural sightseeing at Sanctuary of Saint Peter Claver and Scuba & Snorkeling. You'll discover tucked-away gems like Torre del Reloj and Plaza Bolivar. There's still lots to do: examine the collection at Choco Museo, take in the spiritual surroundings of Convent of Santa Cruz de la Popa, and steep yourself in history at Plaza Santo Domingo.

For traveler tips, photos, reviews, and tourist information, read our Cartagena attractions planner.

Fly from San Andres Island to Cartagena in 3 hours. Expect a daytime high around °C in September, and nighttime lows around °C. Cap off your sightseeing on the 29th (Tue) early enough to travel to Los Roques National Park.

Things to do in Cartagena

Historic Sites Wildlife Outdoors
Find places to stay Sep 26 — 29:
Highlights from your plan
Sanctuary of Saint Peter Claver ©
Sanctuary of Saint Peter Claver
Scuba & Snorkeling
Torre del Reloj ©
Torre del Reloj

1
night
Los Roques National Park, Venezuela

Los Roques National Park ©
Indulge in a relaxing, tropical vacation in Los Roques National Park, a stunning chain of more than 300 coral islands.
Start off your visit on the 30th (Wed): head off the coast to Cayo De Agua. On the next day, step off the mainland to explore Crasqui.

To find other places to visit, maps, and other tourist information, you can read our Los Roques National Park trip planner.

Fly from Cartagena to Los Roques National Park in 11.5 hours. Traveling from Cartagena to Los Roques National Park, you'll lose 1 hour due to the time zone difference. Finish up your sightseeing early on the 1st (Thu) so you can travel to Quito.

Things to do in Los Roques National Park

Parks Nature Outdoors
Find places to stay Sep 30 — Oct 1:
Highlights from your plan
Cayo De Agua ©
Cayo De Agua
Crasqui ©
Crasqui

3
nights
Quito, Ecuador

Quito ©
High in the Andean foothills, Quito remains one of the world's most photogenic capital cities, featuring two dramatic mountain ranges as its backdrop.
Discover out-of-the-way places like Basilica del Voto Nacional and Casa del Alabado. Let the collections at Intinan Museum and La Capilla Del Hombre capture your imagination. There's much more to do: make a trip to Mitad Del Mundo, take an in-depth tour of Museo Templo del Sol Pintor Ortega Maila, admire the landmark architecture of Fundacion Iglesia de la Compania, and appreciate the history behind La Virgen del Panecillo.

To see reviews, maps, more things to do, and more tourist information, you can read our Quito sightseeing planning tool.

You can fly from Los Roques National Park to Quito in 11 hours. The time zone difference moving from Venezuela Time (VET) to Ecuador Time (ECT) is minus 1 hour. October in Quito sees daily highs of °C and lows of °C at night. Finish up your sightseeing early on the 4th (Sun) so you can travel to Cusco.

Things to do in Quito

Museums Historic Sites
Find places to stay Oct 1 — 4:
Highlights from your plan
Casa del Alabado ©
Casa del Alabado
Basilica del Voto Nacional ©
Basilica del Voto Nacional
Intinan Museum ©
Intinan Museum

4
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Get some historical perspective at Sacred Valley of the Incas and Tambomachay. Your cultural itinerary includes sights like Santuario Animal de Cochahuasi and Iglesia de la Compania de Jesus. Step out of Cusco to go to Ollantaytambo and see Archaeological Park Ollantaytambo, which is approximately 1h 50 min away. There's much more to do: trot along with a tour on horseback, wander the streets of San Blas, surround yourself with nature on a nature and wildlife tour, and explore the ancient world of Q'enqo.

To see traveler tips, maps, where to stay, and more tourist information, read Cusco day trip planner.

Traveling by flight from Quito to Cusco takes 8 hours. Alternatively, you can drive; or take a bus. Expect little chillier evenings in Cusco when traveling from Quito in October, with lows around °C. Finish your sightseeing early on the 8th (Thu) to allow enough time to travel to Uyuni.

Things to do in Cusco

Historic Sites Outdoors Tours

Side Trips

Sacred Valley of the Incas, Archaeological Park Ollantaytambo
Find places to stay Oct 4 — 8:
Highlights from your plan
Sacred Valley of the Incas ©
Sacred Valley of the Incas
Horseback Riding Tours
Q'enqo ©
Q'enqo

1
night
Uyuni, Bolivia

Uyuni ©
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
On the 9th (Fri), see the interesting displays at Train Cemetery. Get ready for a full day of sightseeing on the 10th (Sat): take in the dramatic natural features at Salar de Uyuni and then step off the mainland to explore Isla Incahuasi.

For photos, where to stay, other places to visit, and other tourist information, read our Uyuni trip itinerary website.

You can fly from Cusco to Uyuni in 7 hours. Other options are to drive; or do a combination of bus and taxi. The time zone difference moving from Peru Standard Time (PET) to Bolivia Time (BOT) is 1 hour. When traveling from Cusco in October, plan for much colder days in Uyuni, with highs around °C, while nights are about the same with lows around °C. Finish up your sightseeing early on the 10th (Sat) so you can travel to San Pedro de Atacama.

Things to do in Uyuni

Parks Nature Museums
Find places to stay Oct 8 — 10:
Highlights from your plan
Salar de Uyuni ©
Salar de Uyuni
Isla Incahuasi ©
Isla Incahuasi
Train Cemetery ©
Train Cemetery

3
nights
San Pedro de Atacama, Chile

Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.
Step out of the city life by going to Nature & Wildlife Tours and Lagunas Miscanti y Miniques. Do some cultural sightseeing at Pukara de Quitor and Museo del Meteorito. There's still lots to do: see Off-Road Tours, identify plant and animal life at Valle Arcoiris, don't miss a visit to Mirador de Kari, Piedra del Coyote, and witness a stunning natural landmark at Termas Banos de Puritama.

To see where to stay, ratings, more things to do, and other tourist information, refer to the San Pedro de Atacama online trip maker.

Do a combination of taxi and bus from Uyuni to San Pedro de Atacama in 11.5 hours. Alternatively, you can drive. While traveling from Uyuni, expect much hotter days and a bit cooler nights in San Pedro de Atacama, ranging from highs of °C to lows of °C. Wrap up your sightseeing on the 14th (Wed) to allow time to travel to San Carlos de Bariloche.

Things to do in San Pedro de Atacama

Parks Outdoors Tours
Find places to stay Oct 11 — 14:
Highlights from your plan
Nature & Wildlife Tours
Valle Arcoiris ©
Valle Arcoiris
Off-Road Tours

4
nights
San Carlos de Bariloche, Argentina

San Carlos de Bariloche ©
Nestled against the foothills of the Andes, scenic San Carlos de Bariloche hugs the southern shore of Nahuel Huapi Lake and ranks among Argentina's top destinations for active outdoor vacations.
Escape the urban bustle at Parque Nacional Nahuel Huapi and Catedral Alta Patagonis. Discover out-of-the-way places like Piedras Blancas and Parque Nahuelito. There's much more to do: see the interesting displays at Museo del Lago Gutierrez, take a leisurely stroll along Isla Victoria, get a dose of the wild on a nature and wildlife tour, and look for gifts at Chocolates Rapanui.

To see other places to visit, reviews, more things to do, and more tourist information, read our San Carlos de Bariloche trip planner.

Traveling by combination of flight, taxi, and bus from San Pedro de Atacama to San Carlos de Bariloche takes 13 hours. Alternatively, you can do a combination of flight and bus; or drive. Due to the time zone difference, you'll lose 1 hour traveling from San Pedro de Atacama to San Carlos de Bariloche. Traveling from San Pedro de Atacama in October, you will find days in San Carlos de Bariloche are a bit cooler (°C), and nights are about the same (°C). Finish up your sightseeing early on the 19th (Mon) so you can travel to Punta del Este.

Things to do in San Carlos de Bariloche

Parks Outdoors Winter Sports
Find places to stay Oct 15 — 19:
Highlights from your plan
Parque Nacional Nahuel Huapi ©
Parque Nacional Nahuel Huapi
Museo del Lago Gutierrez ©
Museo del Lago Gutierrez
Nature & Wildlife Tours

2
nights
Punta del Este, Uruguay

Punta del Este ©
With plenty of modern casinos, well-developed beaches, chic restaurants, and upscale hotels, Punta del Este vacations draw visitors from Argentina, Brazil, and beyond.
Start off your visit on the 20th (Tue): make a trip to Cerro San Antonio, kick back and relax at Playa Brava, and then make a trip to Puerto de Punta del Este. Keep things going the next day: examine the collection at Museo del Mar, thensnap pictures at Puente Leonel Viera, and then enjoy the sand and surf at Playa Mansa.

You can plan Punta del Este trip in no time by asking Inspirock to help create your itinerary.

You can fly from San Carlos de Bariloche to Punta del Este in 7 hours. Other options are to drive; or do a combination of bus, train, and ferry. While traveling from San Carlos de Bariloche, expect a bit warmer days and much hotter nights in Punta del Este, ranging from highs of °C to lows of °C. Finish your sightseeing early on the 21st (Wed) to allow enough time to travel to Ciudad Del Este.

Things to do in Punta del Este

Outdoors Parks Beaches

Side Trips

Puente Leonel Viera, Cerro San Antonio
Find places to stay Oct 19 — 21:
Highlights from your plan
Playa Mansa ©
Playa Mansa
Playa Brava ©
Playa Brava
Museo del Mar ©
Museo del Mar

1
night
Ciudad Del Este, Paraguay

Ciudad Del Este ©
The commercial center of eastern Paraguay, busy Ciudad Del Este serves primarily as a shopping destination for Argentines and Brazilians.
On the 22nd (Thu), browse the different shops at Nissei and then make a trip to PRESA DE ITAIPU.

To find other places to visit, traveler tips, maps, and other tourist information, read Ciudad Del Este trip planner.

Getting from Punta del Este to Ciudad Del Este by combination of flight and car takes about 9 hours. Other options: drive; or do a combination of bus and car. Plan for somewhat warmer temperatures traveling from Punta del Este in October, with highs in Ciudad Del Este at °C and lows at °C. Wrap up your sightseeing on the 22nd (Thu) early enough to travel to Florianopolis.

Things to do in Ciudad Del Este

Shopping
Find places to stay Oct 21 — 22:
Highlights from your plan
Nissei ©
Nissei
PRESA DE ITAIPU ©
PRESA DE ITAIPU

4
nights
Florianopolis, Brazil

Florianopolis ©
Divided between island and mainland, the distinctive city of Florianopolis charms visitors on first arrival with its impressive skyline.
You'll discover tucked-away gems like Praia do Rosa and Itapema Beach. Escape the urban bustle at Guarda do Embau Beach and Lagoinha do Leste. Explore the numerous day-trip ideas around Florianopolis: Bombinhas Beach (in Bombinhas) and Praia das Laranjeiras (in Balneario Camboriu). There's still lots to do: enjoy the sand and surf at Barra da Lagoa Beach, stroll through Praia Mole, and take a stroll through Costa da Lagoa.

To see ratings, more things to do, reviews, and tourist information, read Florianopolis trip planner.

Traveling by combination of bus and flight from Ciudad Del Este to Florianopolis takes 8 hours. Alternatively, you can drive; or do a combination of car and flight. While traveling from Ciudad Del Este, expect little chillier days and about the same nights in Florianopolis, ranging from highs of °C to lows of °C. Finish your sightseeing early on the 27th (Tue) to allow enough time to travel to Brasilia.

Things to do in Florianopolis

Outdoors Parks Beaches

Side Trips

Bombinhas Beach, Guarda do Embau Beach, Praia do Rosa, Praia das Laranjeiras, Itapema Beach
Find places to stay Oct 22 — 27:
Highlights from your plan
Praia do Rosa ©
Praia do Rosa
Guarda do Embau Beach ©
Guarda do Embau Beach
Barra da Lagoa Beach ©
Barra da Lagoa Beach

3
nights
Brasilia, Brazil

Brasilia ©
Although it lacks the cultural flair of Rio de Janeiro and the massive urban sprawl of Sao Paulo, Brasilia holds a fascinating place in the tapestry of Brazil.
On the 28th (Wed), stroll around Parque da Cidade Sarah Kubitschek, thenget engrossed in the history at Memorial JK, and then contemplate in the serene atmosphere at Santuario Dom Bosco. On your second day here, admire the landmark architecture of Ermida Dom Bosco, take in the views from Juscelino Kubitschek Bridge, and then admire the landmark architecture of Templo da Boa Vontade.

To find reviews, maps, ratings, and more tourist information, refer to the Brasilia tour planning website.

Traveling by flight from Florianopolis to Brasilia takes 5 hours. Alternatively, you can drive; or take a bus. Traveling from Florianopolis in October, you will find days in Brasilia are a bit warmer (°C), and nights are about the same (°C). Finish your sightseeing early on the 30th (Fri) so you can travel back home.

Things to do in Brasilia

Historic Sites Parks Museums
Find places to stay Oct 27 — 30:
Highlights from your plan
Santuario Dom Bosco ©
Santuario Dom Bosco
Templo da Boa Vontade ©
Templo da Boa Vontade
Ermida Dom Bosco ©
Ermida Dom Bosco

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